From multimodal images to connectivity of brain networks in both healthy and pathological conditions

Jesus Cortes

Computational Neuroimaging Laboratory of the Biocruces Health Resarch Insitute

Wednesday, 17.05.2017, 17:00
WW8, Room 2.018-2, Dr.-Mack-Str. 77, Fürth

To study brain functioning and disfunctioning the Computational Neuroimaging Laboratory in Biocruces (Bilbao) is focused on creating and applying brain connectivity methods obtained from magnetic resonance imaging. In particular, we focus on brain networks at the macroscale, thus affecting to the brain as a whole and not to specific brain areas.
While diffusion images provide information about structural connectivity, functional magnetic resonance imaging shed light on resting state functional connectivity [1-3].
In this talk I will focus on recent research focusing on the relationship of both functional and structural networks, and how these methods can be applied to study disconnectivity after a brain insult, such as traumatic brain injury [4-5].

[1] I Diez*, P. Bonifazi*, I. Escudero, B. Mateos, M.A. Muñoz, S. Stramaglia and Jesus M. Cortes (*Equal contribution).
A novel brain partition highlights the modular skeleton shared by structure and function. Scientific Reports 5: 10532, 2015

[2] C Alonso-Montes, I. Diez, L. Remaki, I. Escudero, B. Mateos, Y. Rosseel, D. Marianazzo, S. Stramaglia, Jesus M Cortes.
Lagged and instantaneous dynamical influences related to brain structural connectivity. Frontiers in Psychology 6: 1024, 2015

[3] I. Diez*, A. Erramuzpe*, I. Escudero, B. Mateos, D. Marinazzo, A. Cabrera, E. Sanz-Arigita, S.Stramaglia and Jesus M. Cortes (*Equal Contribution).
Information flow between resting state networks. Brain connectivity 5:554-564, 2015

[4] V Maki-Marttunen*, I. Diez*, Jesus M. Cortes, D.R. Chialvo and M. Villarreal (*Equal contribution).
Disruption of transfer entropy and inter-hemispheric brain functional connectivity in patients with disorder of consciousness. Frontiers in Neuroinformatics 7:24, 2013

[5] Ibai Diez, David Drijkoningen, Sebastiano Stramaglia, Paolo Bonifazi, Daniele Marinazzo, Jolien Gooijers, Stephan P. Swinnen*, Jesus M. Cortes*.
Enhanced pre-frontal functional-structural networks to support postural control deficits after traumatic brain injury in a pediatric population. Network Neuroscience, 2017 (In press). Preprint at https://doi.org/10.1101/057588